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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK6 All Species: 13.33
Human Site: T317 Identified Species: 20.95
UniProt: Q9NQU5 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQU5 NP_001122100.1 681 74869 T317 P S D Q P V G T F S P L T T S
Chimpanzee Pan troglodytes XP_510301 627 67581 G296 V A K G A L A G E D T G V V T
Rhesus Macaque Macaca mulatta XP_001093484 681 74821 T317 P S D Q P V G T F S P L T T S
Dog Lupus familis XP_544614 968 105825 T604 P S D Q P M G T F S P L T S Q
Cat Felis silvestris
Mouse Mus musculus Q3ULB5 682 74848 T318 P S E Q P M G T F S P L T T S
Rat Rattus norvegicus Q62829 544 60692 P213 V V E S I A S P A A P N K E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515215 639 68748 R308 S L H R P P G R P S P A G S P
Chicken Gallus gallus XP_426393 667 74767 Q317 I S D A G T P Q R S P T A E K
Frog Xenopus laevis NP_001082100 650 73749 G312 G S S R P Q Q G Q V K P K P P
Zebra Danio Brachydanio rerio XP_001919719 693 77347 Q317 L V S G G R H Q A S V R S S C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 L308 H P H H H Q H L A K S A S R A
Honey Bee Apis mellifera XP_001122147 624 70155 Q293 A S Q R P L S Q L S T H N V N
Nematode Worm Caenorhab. elegans Q17850 572 63863 I241 R P A R T L S I Y T K P K E E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 G468 T D S S S A N G K F I P S R P
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 P466 F E N P R A P P P V P K G P G
Conservation
Percent
Protein Identity: 100 52.7 98.5 66.4 N.A. 92.5 30.6 N.A. 62.2 75.9 46.7 52.5 N.A. 44.3 44.9 29.8 N.A.
Protein Similarity: 100 60.7 98.9 67.6 N.A. 95.5 48.4 N.A. 69.9 82.3 61.6 64.5 N.A. 57.5 57.5 47.2 N.A.
P-Site Identity: 100 0 100 80 N.A. 86.6 6.6 N.A. 26.6 26.6 13.3 6.6 N.A. 0 20 0 N.A.
P-Site Similarity: 100 20 100 93.3 N.A. 100 26.6 N.A. 40 26.6 20 20 N.A. 13.3 40 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 28
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 41.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 7 7 20 7 0 20 7 0 14 7 0 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 7 27 0 0 0 0 0 0 7 0 0 0 0 0 % D
% Glu: 0 7 14 0 0 0 0 0 7 0 0 0 0 20 7 % E
% Phe: 7 0 0 0 0 0 0 0 27 7 0 0 0 0 0 % F
% Gly: 7 0 0 14 14 0 34 20 0 0 0 7 14 0 7 % G
% His: 7 0 14 7 7 0 14 0 0 0 0 7 0 0 0 % H
% Ile: 7 0 0 0 7 0 0 7 0 0 7 0 0 0 0 % I
% Lys: 0 0 7 0 0 0 0 0 7 7 14 7 20 0 7 % K
% Leu: 7 7 0 0 0 20 0 7 7 0 0 27 0 0 0 % L
% Met: 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 7 0 0 0 0 7 7 0 7 % N
% Pro: 27 14 0 7 47 7 14 14 14 0 54 20 0 14 20 % P
% Gln: 0 0 7 27 0 14 7 20 7 0 0 0 0 0 7 % Q
% Arg: 7 0 0 27 7 7 0 7 7 0 0 7 0 14 0 % R
% Ser: 7 47 20 14 7 0 20 0 0 54 7 0 20 20 20 % S
% Thr: 7 0 0 0 7 7 0 27 0 7 14 7 27 20 7 % T
% Val: 14 14 0 0 0 14 0 0 0 14 7 0 7 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _